The production of Palladium-103 Auger-emitting radionuclides for targeted cancer therapy

Seminar The production of Palladium-103 Auger-emitting radionuclides for targeted cancer therapy
Lecturer

Laouameria Nour Aicha

HUN-REN ATOMKI
Time 2024-03-28 11:00
Place HUN-REN ATOMKI, visitor center
Description of event

Auger-emitting radionuclides, exemplified by Pd-103, exhibit considerable therapeutic potential in cancer treatment due to their high cytotoxicity and localized biological impact. Despite these advantages, the separation of such radionuclides presents a complicated challenge, requiring intricate and time-intensive “wet chemistry” methods attributed to the exceptional chemical inertness of the associated metals. Our study proposes an innovative solution to this separation challenge through the design and implementation of a radionuclide separation equipment (RSE). The equipment employs a dry distillation approach, capitalizing on differences in partial vapor pressures between irradiated and resulting radioactive metals, with a diffusion-driven extraction method applied to separate Pd-103 radionuclides generated via the proton irradiation of Rh-103 at cyclotron.

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